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diagnosis rheumatology dermatology erythematosus sle causes msk pain systemic arthritis algorithm classification infections myopathy myositis oncology physicalexam signs skin symptoms
Tick Borne Illnesses • Lyme (Borrelia) • Babesiosis (Babesia) • Human Monocytic Ehrlichiosis (Ehrlichia) • Human
Mountain Spotted Fever ... Rickettsia) - VA Joint ... Borne #Illnesses #differential ... #diagnosis #comparison ... #table #infectiousdiseases
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Fever, No muscle ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Pain - Differential ... • Rheumatic Fever ... Arthritis • Systemic Lupus ... • Rheumatic Fever ... JointPain #MSK #Differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... • Rheumatic fever ... lesions • Discoid lupus ... #joint #pain #skin ... #rashes #differential
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... acute rheumatic fever ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... Malignancy: - Hematologic ... . autoimmune): Lupus ... , Factitious fever
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Constitutional domain: Fever ... in at least 2 joints ... pericarditis • Hematologic ... Erythematosus #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... phenomenon (20%) Joints ... Arthritis in small joints ... Thrombocytopenia #Lupus
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever ... #pain #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
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