36 results
disease treatment differential erythematosus lupus oncology signs sle classification stills symptoms vasculitis adultonset aosd autoimmune dermatology myositis activation acute adult
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... (SLE) General: Fever ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... weakness, less systemic ... anti-synthetase syndrome ... /full triad at diagnosis ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Differential Diaqnoses ... solid cancers • Systemic ... #management #treatment ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... acid, Elevated Cr ... #TLS #diagnosis ... #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Genitourinary system ... Cardiovascular system ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... malignant) to diagnose ... episode (30%) Systemic ... Disease #AOSD #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Differentiation #Syndrome ... #management #hematology
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