52 results
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
1-3 ([GFR] >30 mL ... 4-5 (GFR < 30 mL ... #Pathophysiology ... #Nephrology #CKD
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
fibrin clot - Treatment ... interaction - Treatment ... minutes after MA/MCF ... - Treatment: ... #coagulation #hematology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the Treatment ... Nonpharmacologic Treatments ... Pharmacologic Treatments ... nalfurafine 2.5 mcg ... #management #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... diagnosis #management #treatment
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Mean eGFR - 39.5 mL ... /min • <60 mL/ ... follow-up • eGFR ml ... Vasculitis #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... sIL-2R >2400 Ul/ml ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment ... Transfusion #Reactions #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Low calcium • Treatment ... diagnosis #management #hematology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... Ferritin <100 ng/mL ... Ferritin 100-299 ng/mL ... functional ID) Treatment