30 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... #medications #druginduced
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Heart Failure (CHF ... depot iron] Treatment ... Heart #Failure #CHF ... #pharmacology # ... pathophysiology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Syndrome - Causes and Treatment ... transformation (CML ... Phlebotomy - MH/CCF ... Syndrome #Causes #Differential ... #Diagnosis #Treatment
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... (0.5 - 0.8 ng/mL ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Kat_Watson #DrugInduced ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... Ferritin <100 ng/mL ... Ferritin 100-299 ng/mL ... functional ID) Treatment ... iron #deficiency #CHF
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... diagnosis #comparison #table
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... per day until stable ... Summary #causes #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... sepsis), PE, DAH, CHF ... Renal Failure Treatment