22 results
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Amphoterecin B, Abelcet ... Drug of choice for ... voriconazole is drug ... #Pharmacology #Antibiotics ... #Review #Overview
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... (e.g. cancer, infection ... suppression (e.g. drugs ... G6PD deficiency), Infections
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
with new bugs & drugs ... CriticalCare #Overview #Pharmacology ... Comprehensive Review ... of Infectious Diseases
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Rapidly cidal drug ... skin/soft tissue infections ... cidal nature) #Pharmacology ... #Antibiotics #Review
Checklist for Evaluation of New-Onset Delirium in the ICU

Initial assessment 
 - 
Vital signs, neuro exam
glucose - Review ... medication list - Review ... /Mg/Phos - CBC ... - Relevant drug ... Additional tox/infectious
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Differential Diagnosis Infectious ... , Candida Non-Infectious ... : • Rheumatologic ... Takayasu Disease, Behcet ... Dissection, Idiopathic, Drug-related
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
gram positive infections ... Drug of choice for ... gram positive infections ... #Pharmacology #Antibiotics ... #Review #Overview
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
severe fungal infections ... severe candidal infections ... - Drug levels ... #Pharmacology #Antibiotics ... #Review #Overview
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... →Activation of CD8 ... Still disease, Infection ... immune deficiency, Drugs ... treatment #summary #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
IgA-associated vasculitis, Behcet ... Disease • Other: Drugs ... allopurinol), Infection ... Investigations • Labs: CBC ... DAH, rule out infection