12 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... DILI and Type of Liver ... Injury #Medications ... #Differential # ... #Pharmacology #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... , HSV, VZV • Medications ... valproate, azoles), Drugs ... MDMA), Alcohol, Iron ... #Diagnosis #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Volume (<80 fL) • Iron ... Renal Disease, Liver ... Deficiency • Drugs ... Algorithm #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Toxic: Alcohol, Medication ... , Recreational Drugs ... #Injury #Differential ... Acute #algorithm #hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... inflammation) • Iron ... Orotic aciduria, Drugs ... Non-megaloblastic: Liver ... #Diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... suppression (e.g. drugs ... #anemia #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... disorders, Oxidative drugs ... elliptocytosis, Severe iron ... RBC #Morphology #differential ... #diagnosis #hematology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... DrugInduced #Edema #Medication ... #Causes #Differential ... #Pharmacology # ... Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Homeostasis In the liver ... The gout drug pegloticase ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management