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diagnosis hematology disease hemolysis management rheumatology agglutinin antibody celiac cirrhosis clinicopathology cold endocrinology erythematosus extravascular extrinsic gastroenterology gestationalage gout growthrestriction
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... would be autoimmune ... #Classification ... Intrinsic #Extrinsic #Differential ... #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... Coombs • IgG type ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential ... idiopathic, malignancy, autoimmune ... #Anemia #Differential ... #causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... Cold AIHA • Alloimmune ... anemia •
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Infection) High ... #MCV #Classification
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... younger pts) Differential ... • Symptoms: High
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Diagnosis Algorithm ... Leukemia (CML) - Hemolytic ... Anemia - Others ... Drug-induced • High ... endocrinology #causes
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis Algorithm ... Iron-deficiency anemia ... without discernable cause ... microscopic colitis Differential ... • Lymphoma • High
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... in Cirrhosis - Differential ... Inflammation NORMAL / HIGH ... , Autoimmune hemolytic ... anemia, Hemolysis
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... #Diagnosis #Differential ... #Causes
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