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diagnosis hematology extravascular intravascular mcv atlas bloodcell calculation cirrhosis decrease dehydrogenase dm2 elevated elevation false hba1c hepatology hgba1c high hyperkalemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... Immune mediated hemolysis ... hemolytic anemia ... #Anemia #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... hemolytic anemia ... G6PD deficiency) ... #differential # ... diagnosis #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Hemolytic Anemias ... • Early Iron Deficiency ... #Normocytic #Anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... immune-complex hemolytic ... anemia •
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
to Anemia - Differential ... Sideroblastic anemia ... -100): • Non-hemolytic ... ACD, Aplastic anemia ... , CKD • Hemolytic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... • Bleeding • Hemolysis ... Marrow Failure • Anemia ... • Folate Deficiency
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... disorders (e.g. autoimmune
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... Vitamin B12 or Folate ... Hemolytic Anemia ... hemolytic anemia ... hemolytic anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
, Vitamin B12, Folate ... Retroperitoneal, Uterine • Hemolysis ... : Autoimmune, Microangiopathic ... hemolytic anemia ... #differential #
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... , Folate deficiency ... syndrome, Spur cell anemia ... , Autoimmune hemolytic ... anemia, Hemolysis
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