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diagnosis causes hematology hemolytic thrombocytosis acidosis anemias approach decrease disorders dm2 extravascular false fetal hba1c hemolysis hgba1c high hospitalization hyperkalemia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... : Membrane defects ... #Differential # ... Diagnosis #Algorithm
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False Elevation ... HbA1c == False Elevation ... • Hemolytic anemia ... E Dilutional Effect ... Diagnosis #DM2 #Differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... #MCV #Classification ... #Differential # ... Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... ITP • Rebound effect ... Iron deficiency anemia ... #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... #Classification ... #Approach #Differential ... #Diagnosis #Algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Diagnosis Algorithm ... immune-complex hemolytic anemia ... Extravascular #Differential ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • Membrane defects ... #Differential # ... Diagnosis #causes #classification
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hemolysis, deficiency anemia ... , Rebound effect ... Lymphoma, Rebound effect
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
Factors that May Affect ... Oxygenation - Differential ... Diagnosis Algorithm ... Capacity: • Fetal anemia ... : • Maternal anemia
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