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diagnosis differential management symptoms erythematosus sle systemic thrombocytosis activation aplastic arteritis autoantibodies cancer causes chronic cll gca giantcell hemeonc hemolytic
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias ... #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... megaloblastic anemia ... SCVMCMed #Aplastic #Anemia ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... effect following treatment ... Iron deficiency anemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... Diagnosis and Lupus ... autoantibodies #signs ... #differential #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... Treatment of GCA ... them, but urgent rheumatology ... GCA #Temporal #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
search for and treatment ... Presentation • Common Signs ... - Cytopenias (anemia ... Treatment Approach ... Diagnosis #Management #Hematology
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