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diagnosis differential management dermatology oncology classification secondary vasculitis bleeding bruising cardiology erythematosus generalized hepatology lupus pruritus sle treatment workup acute
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Gaucher's Disease ... Glycogen Storage Disease ... • Lymphoma • Leukemia ... • Sickle Cell Disease ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... : • Leukemia • ... and Autoimmune Diseases ... : • Systemic lupus ... Differential #Diagnosis #Hematology
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Primary Dermatologic Diseases ... Disease • ... Inflammatory bowel disease ... more than Crohn's disease ... #causes
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... : Cancer, Histiocytic ... Differential #Diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Primary Causes ... Cholestatic liver disease ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... Psychiatric Disease
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... : EGPA, Horton Disease ... , Takayasu Disease ... Primary: Lymphoma, Leukemia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... ASA) • Renal Disease ... Von Willebrand's Disease ... Iatrogenic) • Liver Disease ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... lymphoid organs When Cancer ... #Hematology #Oncology
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