17 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... hemolytic uremic syndrome ... , Hematology 2012 ... #Diagnosis #Differential
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic Microangiopathies ... - Primary Thrombotic ... Diagnosis Table • Thrombotic ... Thrombocytopenic ... MatthewHoMD #Thrombotic
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... testing for TTP #Thrombotic ... #thrombocytopenia ... Diagnosis #Table #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Arterial and Venous Thrombosis ... TTP - Arterial thrombosis ... sites of venous thrombosis ... - MAHA: TTP, HUS ... Arterial #Venous #Thrombosis
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... (ST-HUS) - ... - Drug-induced thrombotic ... #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Venous Thrombosis ... vs Arterial Thrombosis ... Hematological: - HIT ... • Nephrotic Syndrome ... Heparin-induced thrombocytopenia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS •
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
- Thrombotic ... microangiopathy: Thrombotic ... thrombocytopenic ... (HUS) • Other ... Extravascular #Causes #differential
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... Microangiopathy: DIC, TTP, HUS ... antiphospholipid syndrome ... #Differential #
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... triad of MAHA + thrombocytopenia ... association of TMA and HIV ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology