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Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
• Pre-Renal: NSAIDS ... , Antibiotics, NSAIDs ... differential #diagnosis #algorithm ... #nephrology #Medications
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Differential Diagnosis Algorithm ... eosinophiluria) • Drugs (NSAlDs ... KidneyDisease #Nephrology ... Differential #Diagnosis #Algorithm
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Nephrotoxins (NSAlDs ... AcuteKidneyInjury #AKI #Nephrology ... #Diagnosis #Algorithm
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Differential Diagnosis Algorithm ... Conn's syndrome • NSAlDs ... HTN #Secondary #Nephrology ... Differential #Diagnosis #Algorithm
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Differential Diagnosis Algorithm ... Nephritis • Drugs (NSAlDs ... #KidneyInjury #Nephrology ... Differential #Diagnosis #Algorithm
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... antagonism • NSAlDs ... IntercellularShift #Nephrology ... Differential #Diagnosis #Algorithm
NSAID vs ACEI/ARB effects on the Kidneys Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... Remember that NSAIDs ... kidney function, NSAID ... /ambcarerx #NSAIDs ... ACEIARB #Effects #Nephrology
NSAID Pharmacology - Amy Chung, MD, MSc @AmyChung #NSAIDs #Pharmacology #COX #Cyclooxygenase
NSAID Pharmacology ... @AmyChung #NSAIDs
NSAID Selectivity Spectrum COX-2 Selective NSAID - Celecoxib • Increased risk for CV events • Decreased risk
NSAID Selectivity ... COX-2 Selective NSAID ... Semiselective NSAIDs ... risk Nonselective NSAIDs ... side effects #NSAIDs
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 Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis - Renal disease, Cardiovascular disease -> Decreased renal
Renal Effect of NSAIDs ... Vasopressin NSAlDs ... #NSAIDs #Prostaglandins
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