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hematology differential table clinical hemolytic anemia algorithm hemolysis management causes cold covid19 gout lung msk oncology radiology appearance contrast extravascular
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Differential Diagnosis ... (7-8%) DAT-negative ... #Differential #Diagnosis ... #Table #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... C3 positive or negative ... #Autoimmune #Hemolytic ... Pathophysiology #diagnosis ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia 1) DIAGNOSE ... AIHA • Anemia ... screening 3) TREAT AIHA ... management #treatment #rheumatology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... Hemolysis DAT Negative ... ), C3d ( - ) WAIHA ... #Hemolysis #hematology ... #diagnosis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... Hemolysis: • Autoimmune ... Hemolytic Anemias (AIHAs ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... • Cold AIHA ... • Alloimmune ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... AIHA, Transfusion ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (AIHA) "Warm" ( ... (AIHA)"Cold" (usually ... #differential #diagnosis ... #hematology #anemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Atypical HUS, autoimmune ... atheroembolic, AIHA ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Hemolytic Anemia Warm Autoimmune ... Splenectomy Cold Autoimmune ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
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