83 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... #Pharmacology #Pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... in Sickle Cell Disease ... number of pain crises ... Benefits #SickleCell #pathophysiology ... #pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Tubular Proteinuria (Negative ... (MPA) • SLE ... Minimal change disease ... Diagnosis #Algorithm #Causes
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess ... antibiotics as a cause ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
treat infectious diseases ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
fastidious gram-negative ... Culture & GS, PCR Treatment ... : • Severe Disease ... diagnosis #management #treatment ... #infectiousdiseases
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... fusiform gram-negative ... Treatment: • 50% ... microbiology #zoonotic #infectiousdiseases