13 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... distal component of Nephron ... blood flow: Pre ... #pathophysiology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Tubular Defects ... #Localization #Nephron ... #Defects #Pathophysiology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... through distal nephron ... Creatinine • Chronic renal ... #Hyperkalemia #IntercellularShift ... Differential #Diagnosis #Algorithm
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Direct effect to ... excretion in distal nephron ... Nonhemodynamically mediated effects ... AngiotensinII #Pathophysiology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... • Increased renal ... Hypoperfusion • Reduced renal ... blood flow • ... syndrome #Mechanisms #pathophysiology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Primary polydipsia, Low ... solute intake, Renal ... Helbert Rondon, MD @NephroMD ... #differential #algorithm
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Differential Diagnosis Algorithm ... Malabsorption RENAL ... Hypercalcemia-PTH effect ... Hypomagnesemia #Magnesium #Low ... Differential #Diagnosis #Algorithm
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... arteriole in the nephron ... Tubular Poisons (Low ... tubule in the nephron ... Hyperuricemia #Pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Renal Effect of ... Synthesis - Renal ... disease -> Decreased renal ... blood flow - ... #Pharmacology #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Decreased Intake: • Low ... - Diarrhea • RENAL ... gas transport, renal ... #Pathophysiology