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diagnosis differential algorithm causes autoimmune erythematosus hemolysis lupus oncology rbc systemic atlas classification extravascular intravascular leukemia management mcv microscopy morphology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... #Autoimmune #Hemolytic ... #Anemia #AIHA # ... Diagnosis #Table #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Anemias (AIHAs) ... Anemias (AHAs) ... Diagnosis #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
• Cold AIHA ... Defects • G6PD deficiency ... • PK deficiency ... anemia • ... Algorithm #Causes #Hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... #Autoimmune #Hemolytic ... #Anemia #Pathophysiology ... #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... screening 3) TREAT AIHA ... management #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... - Autoimmune (AIHA ... G6PD deficiency) ... differential #diagnosis #hematology ... #anemia
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA # ... Treatment #management #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
RA, SLE, PRV, Chronic ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... • Early Iron Deficiency ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... • Severe B12 deficiency ... anemia" • HELLP ... differential #diagnosis #hematology ... #hemolysis
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... anemia (e.g. ... Microspherocytes: Autoimmune hemolytic ... Bite cells: G6PD deficiency ... Smear #Analysis #hematology
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