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hematology differential causes treatment dermatology pruritus systemic cll generalized lymphocytic mds myelodysplastic secondary syndrome approach bacilliformis bartonella blood calculation chagas
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Fatigue • Acute ... Age > 50 • Chronic ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... leukemia • Associated ... #Anemia #diagnosis ... #management #treatment
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Loss • Acute ... Deficiency • Aplastic ... of Chronic Disease
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... • Marrow Aplasia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... #Anemia #oncology ... #management
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Artifact (redo CBC ... Myelogenous Leukemia ... Infectious: • Acute ... Iron deficiency anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... Pure red cell aplasia ... ’s lymphoma or acute ... #oncology #hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Differential Diagnosis ... Algorithm Primary ... Disorders • Acute ... (ALL) • Acute ... - Hemolytic Anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Chronic ... marrow failure: Aplastic ... Index > 3: • Acute ... #differential #diagnosis
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