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diagnosis differential management algorithm workup rheumatology syndrome classification thrombocytosis arthritis disorders leukemia secondary aplastic approach atlas cll disease elevatedmcv generalized
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Loss • Acute ... • Anemia of Chronic ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Fatigue • Acute ... Age > 50 • Chronic ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... blood loss), Vitamin ... Index > 3: • Acute ... blood loss: Trauma ... Production #Index #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , Chronic disease ... disease, McLeod blood ... myeloma Rouleaux: Chronic ... differential #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic kidney ... disease, Acute ... blood loss, Anemia ... differential #diagnosis #causes ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , deficiency anemia ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Deficiency (Eg Causes ... : Chronic Blood ... TlBC > 18% • Anemia ... #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Myelofibrosis • Chronic ... Differential #Diagnosis #causes ... #Platelets #hematology
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