33 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... #Morphology #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... Iron deficiency anemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Differential # ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... Fatigue • Acute ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Chronic ... Index > 3: • Acute ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... , deficiency anemia ... • Infections: Chronic ... Thrombocytosis #Platelets #Differential