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diagnosis nephrology differential potassium management treatment criticalcare diuretics foamed hyperkalemia medications acutekidneyinjury aki chf classes clinical conversion crystalloids digoxin diuresis
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Increased EC shift of K ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #nephrology #causes
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
Algorithm for patients ... • Low Urine Cl ... • High Urine Cl ... #differential #algorithm ... #diagnosis #nephrology
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
/Cl-,• secondary ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Antibiotics (Bactrim, PCN ... only if no clear cause ... Elimination (see Table ... Ca-gluconate or 1g CaCl ... Treatment #potassium #nephrology
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... - Hyperkalemia ( ... #cardiology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Urine Na/K/ ... Cl/urea/protein/ ... rhabdo/TLS) Causes ... #Diagnosis #Algorithm ... #Causes #Differential
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Vomiting: urine Na/Cl ... 1.6, low urine Cl ... 0.7, high urine Cl ... Tubulopathy: urine K/ ... with urine Na/Cl
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
its Chloride (Cl ... are balanced by Cl ... high amount of Cl ... in the ECF causes ... Hyperkalemia, a
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... • Inhibit Na+K+ ... #nephrology #conversion ... loop #thiazide #classes
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