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rheumatology infectiousdiseases syndrome microbiology differential hepatology dermatology neurology algorithm sle summary classification erythematosus oncology systemic vasculitis chagas fungal gastroenterology infections
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
+/- diarrhea Diagnosis ... • Hantavirus PCR ... • Autopsy PCR ... Treatment: • ... #management #treatment
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... With associated pulmonary ... #differential #diagnosis
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management Caused by: Tropheryma whipplei Symptoms and Signs: 1. Migratory poly/oligoarthralgia
Whipple Disease ... and Management ... Caused by: Tropheryma ... whipplei tests (PAS, PCR ... whipplei test (PAS, PCR
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... of PCN allergy ... Lung #Abscess #pulmonary ... #differential #causes ... #management #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... but elevated as disease ... Diagnosis: • ... #workup #hepatology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia Differential Diagnosis ... Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... disease, Smoking ... #Algorithm #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... Evolution: Chronic disease ... #diagnosis #management
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