16 results
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... be normal. 1:1 Mix ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Factor XI, IX ... elevated in: • DIC ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... Drug-associated, PCH ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Deficiency of Factor IX ... Post-partum • Acute DIC ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Elevated Liver tests ... schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... SEROSITIS - RENAL - NEUROLOGIC ... ANA level above laboratory ... Direct Coombs’ test ... #Rheumatology #
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Elevated Liver tests ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Disorientation, vertigo Diagnostic ... test, TempTest ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Laboratory ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... (to support a diagnosis ... #workup #diagnosis ... #testing #Rheumatology