41 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Scl70 (in some cases ... ARUPLabs #ANA #Antinuclear ... #differential #diagnosis ... #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... Warm AIHA • Cold ... AIHA • PCH ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... practices that could ... K), H. pylori test ... thyroid function test ... #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... Jcortesizaguirr #ANA #Antinuclear ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Hemoglobinuria (PCH ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH ... Laboratory Tests ... #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Scl70 (in some cases ... ARUPLabs #ANA #Antinuclear ... #differential #diagnosis ... #rheumatology
Abdominal Pain - Differential Diagnosis According to Localization of Abdominal Pain 

Abdominal pain can originate from
GI, infectious, hematologic ... extra-abdominal causes ... abdominal pain (Table ... exhaustive and should ... GrepMed Recommended Text
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... suspected, tests ... erythematosus #diagnosis ... #rheumatology # ... table #ANA