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diagnosis differential arterial extravascular hemolysis venous anemia clots coagulation deficiency dic disseminated embolism emergencies erythrocytosis fe hemeonc hemolytic iron management
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PCH • PNH ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... syndrome - Thrombotic ... microangiopathy: Thrombotic ... hemoglobinuria (PNH ... #diagnosis #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... - Disseminated intravascular ... APLS:PLT ↓ HEMATOLOGIC ... neoplasms - PNH
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all cases ... - Disseminated intravascular ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treat primary cause ... #Disseminated #Intravascular ... Coagulation #diagnosis #causes ... treatment #management #hematology
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... • Iron loss: Intravascular ... hemolysis, (PNH ... athletic training, Pulmonary ... #Fe #algorithm
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Differential Diagnosis Algorithm ... Splenomegaly, Increased PMNs ... Cyanosis without Pulmonary ... #Causes #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
May develop in pts ... tract, and often causes ... Thrombosis and arterial ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... (disseminated intravascular ... Treat underlying cause ... ) - Symptoms: CNS ... renal failure, pulmonary
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