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diagnosis treatment differential syndrome algorithm reactions blood cardiology erythrocytosis nephrology pharmacology polycythemia product transfusion antinxp2 antinxp2dm apml capillary cardiomyopathy chf
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... - Water - Pus ... Vasculature: - PE - Pulmonary ... Transverse myelitis • Hematology ... #pulmonary
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Splenomegaly, Increased PMNs ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... , and CXR with pulmonary ... edema) • Fever ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Hypoxia-independent: Post-renal ... Diagnosis #Algorithm #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Bleeding (64%) • Renal ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
myalgias, HoTN, edema ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... APML #diagnosis #management ... #hematology #oncology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... irrigation • Management ... Torsemide) • Acute pulmonary ... Kidney stones caused ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
S/Sx: Most pts ... 15 suggests ↓ renal ... only if no clear cause ... Elimination (see Table ... caution in HTN & edema
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... Distal (Type I) renal ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
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