24 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... Management #treatment #hematology ... #oncology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... invade URT & via hematologic ... induces vascular & CNS ... CNS and hematologic ... peds #pediatrics #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... cardiovascular risk ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... showed reduced risk ... endpoint of all-cause ... diagnosis #management #cardiology
Commotio Cordis 
- Commotio cordis occurs when an object strikes the chest over the heart. It
It can cause sudden ... commotio cordis risk ... Cordis #Diagnosis #Pathophysiology ... #Cardiology #Sudden
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... without other cause ... transfused patients • Risk ... Transfusion #Reactions #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... with an increased risk ... • Increased risk ... Differential #Diagnosis #Pathophysiology ... #causes #cardiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Attempt if high risk ... diagnosis #management #hematology ... #oncology