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hematology differential algorithm hemolytic causes thrombocytopenia hemolysis workup autoimmune oncology aflp aiha atlas deficiency disorders extravascular hus intravascular management microangiopathy
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... - Differential Diagnosis ... Table Warm AIHA ... Matthew Ho, MD PhD ... #Table #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... BostonChiefs #Warm #Cold ... #hematology #diagnosis ... #comparison
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Matthew Ho, MD PhD ... #Differential #Diagnosis ... #Algorithm #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... Pathophysiology - Warm vs Cold ... Smear: spherocytes Cold ... Pathophysiology #diagnosis ... #hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... Matthew Ho, MD PhD ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... hepatomegaly • Labs: anemia ... Matthew Ho, MD PhD ... #Algorithm #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • AIHA: warm, cold ... TTP, HUS, DIC, HELLP ... classification #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Matthew Ho, MD PhD ... #Algorithm #hematology
Thalassemia - Electrophoresis - Comparison Table In this disorder it is the defective production of hemoglobin that
Electrophoresis - Comparison ... Table In this ... #Alpha #Beta #Comparison ... #Table #Hematology ... Electrophoresis #Diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... TTP, HUS, DIC, HELLP ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... #hematology
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