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diagnosis hematology anemia causes microscopy atlas bloodcell clinical extravascular ferritin index interpretation intravascular iron morphology nomenclature normocytic peripheral platelets production
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Immune mediated hemolysis ... hemolytic anemia ... UnremarkableLab #Hemolytic ... #Anemia #Differential
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Schistocytes: Microangiopathic ... hemolytic anemia ... Microspherocytes: Autoimmune hemolytic ... Bite cells: G6PD deficiency
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... immune-complex hemolytic ... malformations #Hemolysis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Bleed • Hemolysis ... Fragments • Microangiopathic ... Hemolytic Anemias ... • Early Iron Deficiency ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... : Autoimmune, Microangiopathic ... hemolytic anemia ... #anemia #differential ... #diagnosis #calculation
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Schistocyte: Microangiopathic ... Hemolytic Anemia ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... TSAT, sTfR • Blood ... extravascular) hemolysis ... #Anemia #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hematologic: Acute blood ... loss, Acute hemolysis ... , deficiency anemia
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