36 results
diagnosis differential causes algorithm hypokalemia management metabolic alkalosis hyperkalemia low medications pathophysiology syndrome action gitelman high hypomagnesemia kidney nephron sites
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
Diuretics sites ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Renal Actions of Diuretics #Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Diuretics #Diuretics ... Action #Nephron #Pharmacology ... #Nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Pharmacology # ... nephrology #conversion
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
minutes) Decrease potassium ... Fluids Shift potassium ... (if preserved renal ... function) - Loop diuretic ... #nephrology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Potassium Excretion ... Aldosterone Release: ACE ... Pathophysiology #Pharmacology ... #Renal
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Medications Renal ... Losses Non-renal ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypertensive: • High Al ... aldosteronism • High Al ... >20 mEq/24 h - Diuretics ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... Loop and thiazide diuretics ... Algorithm #causes #potassium ... #low #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Regulating Renal ... Inhibitors of Na+K+2Cl ... #Renal #Excretion ... #Diuresis #Nephrology ... #Pharmacology #
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