14 results
Lisinopril - ACE inhibitor used for the treatment of hypertension and heart failure. 3rd most prescribed
Lisinopril - ACE ... #Pharmacology #Lisinopril ... Prinivil #Qbrelis #ACEI ... Inhibitor #Overview #Review
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin-converting enzyme (ACE ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
thiazides) - Gout ... , Hypokalemia, Erectile ... higher risk of hyperkalemia ... (ACEI, ARB, diabetes ... ) ACE inhibitors
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Lymphoblastic Leukemia (ALL ... Myeloid Leukemia (AML ... Sarcoidosis • Hypercalcemia ... drugs • ACE ... • Alcohol #gout
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
Here’s a review ... classes (Aliskiren, ACEI ... Antagonists), all ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Gout: Pathogenesis ... Medications (ASA, ACE ... Chronic tophaceous gout ... Hyperuricemia #Pathophysiology ... Complications #Gout
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Complications - Hypercalcemia ... renal tubules - ACE-inhibitors ... Hyperuricemia #Pathophysiology ... Complications #Gout
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... offending medications (review ... Ca-gluconate or 1g CaCl ... for cations in gut ... measures Check out
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... who have chronic hyperkalemia ... ACE inhibitors, ... carry the risk of hyperkalemia ... #Pharmacology