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diagnosis causes management syndrome algorithm hematology rheumatology anesthesia anesthesiology checklist intraoperative workup ana antibody antinuclear druginduced erythematosus hyperkalemia induced lupus
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
syndrome (TLS) - Pathophysiology ... cytotoxic therapy of ALL ... , AML, NHL → AKI ... syndrome #TLS #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome #APML
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Lymphoblastic Leukemia (ALL ... Myeloid Leukemia (AML ... drugs • ACE ... Hyperuricemia #Differential
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Acute • Myloid (AML ... • Lymphoid (ALL ... hematology #Markers #Differential
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... : - Catch-all term ... range of potential pathophysiologic ... - Pathophysiology ... Targetoid #Algorithm #Differential
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... ) 30-45% Differential ... symptoms #mimickers #differential
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
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