15 results
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... #Bleeding #Bruising
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
of Bleeding / Bruising ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Thromboelastogram ... representing thrombin-platelet ... - Treatment: Platelets ... rishikumarmd #Thromboelastogram ... Thromboelastography #diagnosis #coagulation
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Hematology #Management #Table
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Symptoms: B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastography #Thromboelastogram
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... hematology #diagnosis #table
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... Excessive bruising ... lowest levels Platelet ... ability to bind platelets ... Measurement of coagulation
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... nickmmark #TEG #Thromboelastogram