19 results
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... - Differential Diagnosis ... Algorithm • Vascular ... vs Acquired • Platelet ... Qualitative • Coagulation
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Thromboelastogram ... representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastography #diagnosis ... #coagulation #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Sequestration Disordered Platelet ... #Algorithm #Causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... Findings: • Bleeding ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... #diagnosis #causes
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Algorithm Features ... B-symptoms, bruising/bleeding ... anemia, ↑ MCV, ↑/↓ platelets ... #Algorithm #hematology
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... lowest levels Platelet ... Diagnosis VWF ... ability to bind platelets ... Measurement of coagulation
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... hemorrhage, while under-coagulation ... #management #algorithm ... #medications #table
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastography #Thromboelastogram
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... obstetrics #hematology #diagnosis ... #table #comparison