61 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Anemia (AIHA) Pathophysiology ... , C3 positive or ... IgG negative, C3 positive ... Hemolytic #Anemia #Pathophysiology ... #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
autoantibodies: positive ... → schizocytes, Positive ... diagnosis #management #treatment ... #rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Findings: Coombs positive ... Spherocytes • Treatment ... Findings: Coombs Positive ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... heart failure, positive ... : No • Treatment
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
joint) - 5 points Serology ... points Low positive ... RF or low positive ... RF or high positive ... Classification #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... diagnosis #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
- Anti-ENA - Positive ... - Anti-dsDNA - Positive ... Anti-histone - Positive ... life-threatening • Treatment ... Management #Summary #rheumatology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
mobilization or supine position ... Pathophysiology: ... Treatment: anticholinergics ... PhysicalExam #clinical #neurology
Phimosis 
Inability to retract the foreskin - Can be normal up to 3 years old -
after age 4 Treatment ... back to anatomic position ... Comparison #Diagnosis #Urology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Anti-histone - Positive ... constitutional symptoms • Treatment ... - Anti-dsDNA - Positive ... life-threatening • Treatment ... comparison #table #rheumatology