324 results
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is.  The R0
Reproductive Number (R0 ... The R0 for Wuhan ... Diphtheria R0 ... Fatality 2-3% ** 'Ro ... #Ro #RNaught #Contagious
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro ... #Rheumatology #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-SSA (Ro), ... Associations #diseases #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... #Summary #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... 40% Target: SS-A/Ro ... higly specific for SLE ... erythematosus #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lesions • Anti-Ro ... Differential Diagnosis ... • Anti-Smith, Ro ... ANA + (+) anti-Ro ... Erythematosus #Diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
in drug-induced SLE ... Anti-Ro/SSA ... Antineutrophil #antibodies #diagnosis
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... #Rheumatology #Diagnosis
Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria

#Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Diagnostic Criteria ... SLICC Criteria #Diagnosis ... #Rheumatology #SLE
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Levels - C3, C4 • SLE ... • Infection eg SBE ... #differential #diagnosis