2423 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Classification #Approach #Differential
The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes:

Conditions with Abnormal RBCs:
 •
The differential ... with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC ... Elevated #MCHC #Differential
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
== Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... Dilutional Effect • RBC ... Diagnosis #DM2 #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Macrocytes, Normal RBCs ... Spherocytes, RBC ... ) - Abnormal RBCs ... Normocytic #Anemia #Differential
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... • Extrinsic RBC ... • Intrinsic RBC ... Hemolytic #Anemias #Differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... sometimes) Macrocytic RBC ... Bite Cell RBC: G6PD ... #Morphology #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... 3) Internal (RBC ... Smear ↑ abnormal RBCs ... #Hemolysis #Differential
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... #Macroscopic #Differential
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... ischemia-induced RBC ... hemolysis) • RBC ... #Hyperkalemia #Differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Volume (MCV) - Differential ... - Fe/TlBC, MCV/RBC ... TIBC Normal - MCV/RBC ... inclusions in RBC ... #elevatedMCV #Differential