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management differential antibodies disease ana antinuclear classification cryoglobulinemia erythematosus lupus myositis oncology signs symptoms systemic table thrombocytopenia treatment workup 1:
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Damage Through 2 ... : • Clinical triad ... Labs/Diagnosis: ... erythematosus (SLE ... classification #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Others: SRP, Mi-2, ... Autoantibodies #Rheumatology ... #diagnosis #associations
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... not related to clinical ... into 3 types 2) ... Hyperviscosity syndrome ... #Diagnosis #Rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... oral ulcers with 2 ... AND • Meeting ≥ 2 ... test Most Common Clinical ... #criteria #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
manifestations +++ 2. ... dermatomyositis, SLE ... leukocytoclastic vasculitis ... #differential #diagnosis ... #clinical #skin
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... cases • Sjögren syndrome ... ANCA-Associated Vasculitis ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
TIF1y, NXP2, Mi-2, ... SAE Anti-Synthetase ... Syndrome: Jo-1, ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
anti-synthetase syndrome ... at diagnosis). ... Can also see mechanics ... weakness after 2 ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Thrombosis and arterial ... ) - 2 relevant ... , and SLE) • Urinalysis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
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