9 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... Systemic #Lupus #Erythematosus ... #rheumatology #management
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... body-like: - Neurologic ... ARUPLabs #ANA #Antinuclear
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... with MCTD and Raynaud's ... Lupusreference #Antinuclear ... Systemic #lupus #erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... Ulceroglandular: Fever + erythematous ... conditions Diagnosis: Serology ... tularensis #diagnosis #management
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... CTD-ILD, IIM, Raynaud ... body-like: • Neurologic ... ARUPLabs #ANA #Antinuclear
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Systemic lupus erythematosus ... (SLE) - Antinuclear ... • Hepatitis B serology ... Hepatitis B and C serology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Cryoglobulinemia (4%-12%), Raynaud ... Rheumatology #Diagnosis #Management
Powassan Virus Infection
 • Prodrome +/- fine erythematous rash → sudden onset fever, neurological deficits
 •
Prodrome +/- fine erythematous ... Infection #diagnosis #management ... #neurology