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diagnosis rheumatology management ana differential erythematosus systemic antibody patterns cytoplasmic druginduced nuclear table arthritis cerebritis cns comparison dil disease laboratory
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear ... #autoantibodies
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #Systemic #Lupus
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... involvement 3% SLE-Related ... Lupusreference #SLE ... Erythematosus #Diagnosis #autoantibodies
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... the formation of autoantibodies ... Puncture, EEG Treatment ... Erythematosus #SLE ... diagnosis #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... months) and of autoantibodies ... Erythematosus (SLE ... life-threatening • Treatment ... #sle #comparison
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... SSc, PM/SSc OS, Raynaud
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... ) - Antinuclear ... - CCP antibody testing ... and C serology testing ... workup #diagnosis #testing
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... months) and of autoantibodies ... rheumatology #diagnosis #treatment
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