14 results
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies ... ; c-ANCA, cytoplasmic ... antibodies; SLE ... , systemic lupus ... erythematosus.
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... SLE), Sjogren's ... @AnnKumfer #Antinuclear ... #Antibodies #ANA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #SLE #Summary #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Raynaud's phenomenon ... Lupusreference #Antinuclear ... #erythematosus
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... erythematosus ( ... @AnnKumfer #Antinuclear ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic ... Systemic lupus ... erythematosus ... in drug-induced SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... and Cytoplasmic ... SSc, PM/SSc OS, Raynaud ... #Testing #Nuclear
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... Workup: - ANA ... life-threatening • Treatment ... #Erythematosus
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... Auto-Antibodies ... : - ANA 95-100% ... #Erythematosus
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... #Antinuclear #Antibody ... #Testing #Cytoplasmic