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diagnosis table pharmacology clinical management differential radiology cardiology nephrology pathophysiology pocus medications endocrinology pulmonary treatment types algorithm causes syndrome ultrasound
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
Tract: ↑ Ca2+ absorption ... , ↑ PO4- absorption ... , ↑ PO4- reabsorption ... , ↓ PO4- reabsorption ... , PO4- reabsorption
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
↑ intestinal absorption ... ↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption
Fluid and Water Secretion and Absorption in the GI Tract #Fluid #water #Secretion #Absorption #reabsorption #GITract #diagnosis
Secretion and Absorption ... water #Secretion #Absorption ... #reabsorption #
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Miscellaneous - Bone Resorption ... - Calcium Reabsorption
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
Diabeta) 3 CARB ABSORPTION ... slows gut starch absorption ... tubule glucose reabsorption
GI Tract Secretions and Fluid Absorption Dietary Input and Digestive Secretions: • Food and drink: 2000 mL
Secretions and Fluid Absorption ... 200 mL Water Reabsorption ... Secretions #Fluid #Absorption ... #Reabsorption #
NSAIDS and their effects on the Kidney - Pathophysiology Arachidonic Acid metabolites into alternative pathways that modify
• Increase Na reabsorption ... • Increase H2O absorption
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
increased bone Ca2+ resorption ... increased GI Ca2+ absorption
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
tubule (PCT) - Reabsorption ... Isosmotic reabsorption ... Secretion and reabsorption ... loop - Passive reabsorption ... (TAL) - Active reabsorption
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