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diagnosis signs management pathophysiology differential clinical algorithm treatment syndrome neurology comparison cardiology physicalexam pharmacology table causes msk endocrinology video psychiatry
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
↑ intestinal absorption ... ↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
Kidneys: ↑ Ca2+ reabsorption ... , ↑ PO4- reabsorption ... Kidneys: ↑ Ca2+ reabsorption ... , ↓ PO4- reabsorption ... , PO4- reabsorption
Fluid and Water Secretion and Absorption in the GI Tract #Fluid #water #Secretion #Absorption #reabsorption #GITract #diagnosis
Secretion and Absorption ... water #Secretion #Absorption ... #reabsorption #
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview HCO3 reabsorptive failure Lowering of threshold for HCO3 absorption in
Overview HCO3 reabsorptive ... threshold for HCO3 absorption
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Miscellaneous - Bone Resorption ... - Calcium Reabsorption
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
tubule (PCT) - Reabsorption ... Isosmotic reabsorption ... Secretion and reabsorption ... loop - Passive reabsorption ... (TAL) - Active reabsorption
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
action -> Decr Ca2+ Absorption ... Increased Bone Resorption ... pathophysiology #signs #symptoms
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
Diabeta) 3 CARB ABSORPTION ... slows gut starch absorption ... tubule glucose reabsorption
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis: https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext #Pathophysiology #Mechanism #Nephrology
block glucose reabsorption ... SLGT2 #Inhibitors #Reabsorption
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