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Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... (Diffuse) Anti-Sm ... - SLE Anti-SSA
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... ELISA) - Anti-Sm ... of antibody to Sm ... #Rheumatology #SLE
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-dsDNA, Anti-Sm ... #IMDAMNSHARP #sle
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... phenomenon Anti-Sm ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE
SOAP BRAIN MD Mnemonic for Systemic Lupus Erythematosus (SLE) S - Serositis (Pleuritis, Pericarditis) O - Oral Ulcers A
Erythematosus (SLE ... Immunologic (anti-Sm ... Erythematosus #SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... UCTD - Smith, Sm ... Speckled: - SLE ... conditions, SjS, SLE
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... 15-30% - Anti-Sm ... Lupusreference #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... cutaneous DIL), anti-Sm ... Erythematosus (SLE ... are evocative of SLE ... management of SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
antibody, Anti-Sm ... Classification #Criteria #SLE
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-Sm (Smith) ... in drug-induced SLE
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