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diagnosis symptoms differential erythematosus systemic sle management autoantibodies hematology neurology table ana antibodies antinuclear autoimmune complications vasculitis associations bleeding bruising
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... clinical #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #diagnosis #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... • Transverse myelitis ... positive NMO only): Myositis ... disorders (Systemic lupus ... neurology #symptoms #signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... Diagnosis and Lupus ... autoantibodies #signs ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... Adenopathies, Lupus ... Arthralgia / arthritis, Myositis ... Erythematosus #SLE #Signs ... Symptoms #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Diagnosis of Lupus ... CNS #neurology #rheumatology
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