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diagnosis hematology causes algorithm anemia classification hemolysis hemolytic management product vasculitis atlas basophilia basophils comparison dermatologic disorders ebm eosinophil eosinophilia
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Care TRICC - NEJM ... - ICU FOCUS - NEJM ... blood is a liquid ... Blood saves lives ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Reaction (FNHTR ... Reaction (AHTR) ... maculopapular rash ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... maculopapular rash ... in transfused blood ... diagnosis #management #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... hematologic: Acute blood ... Inflammatory Conditions: Rheumatologic ... Diagnosis #Algorithm #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... - Peripheral Blood ... #Diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... plasma volume transfusion ... of high parity blood ... #Reactions #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... Hemolytic #Anemia #Differential ... classification #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... Diagnosis #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
HUS) • Other: Transfusion ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes #differential ... #diagnosis #hematology
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
determining if transfusion ... of blood products ... need for specific blood ... patients) R (reaction ... interpretation #hematology
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