30 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... methotrexate) • Drugs ... Non-lmmune: • HELLP ... Syndrome • TTP/HUS ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... Toxin-Mediated HUS ... HUS (aHUS) ... Complement-mediated TMA - Drug-induced ... Microangiopathy #TMA #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... HemolyticUremicSyndrome #HUS ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- MAHA: TTP, HUS ... , DIC, HELLP ... Membrane Defects, Drugs ... Thalassemias, Unstable ... Differential #Diagnosis #hematology
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... Malignancy, Autimmune, Drugs ... Reactive (Infection, medications ... Neutropenia: Infections, Drugs ... #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
hemolytic-uremic syndrome (ST-HUS ... known as atypical HUS ... ) - Drug-induced ... hemolytic anemia" • HELLP ... differential #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... AIHA: warm, cold, drug ... • MAHA: TTP, HUS ... , DIC, HELLP, AS ... classification #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Production: - Drugs ... Microangiopathy: DIC, TTP, HUS ... - Pregnancy: HELLP ... Diagnosis #Framework #hematology
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... once a suspected drug ... #Diagnosis #Hematology ... #DrugInduced #Medications ... #Causes