14 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
critically ill pregnant ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of Pregnancy ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... Production: - Drugs ... antiphospholipid syndrome - Pregnancy ... #Framework #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Blood Smear • Drugs ... Pregnancy) - Low ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... Sickle cell • Unstable ... #Algorithm #Causes ... #Hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Drugs 5. ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Use • Pregnancy ... • Drugs: - ... coagulation and other causes ... pathophysiology #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... Shiga-toxin HUS, drug-associated ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... ↑ sIL-2R >2400 Ul ... immune deficiency, Drugs ... , Unknown cause ... treatment #summary #rheumatology