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management hematology differential syndrome table comparison lupus sle abscess adultonset algorithm antinxp2 antinxp2dm apml bronchiectasis capillary clarksons classification coagulation consolidation
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... MAS, Visceral, DIC ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
fulminans • Subcutaneous ... • Severe Liver Disease ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... - Differential Diagnosis ... Abnormal Abdominal Ultrasound ... #Algorithm #Causes ... #Hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
- Cr >2 mg/dL or ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Blood cultures • CXR ... ) • CXR upright ... Lung #Abscess #pulmonary ... #differential #causes
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
- Differential Diagnosis ... in 24h Airway disease ... Kaposi's sarcoma • Rheumatologic ... Coagulopathy: DIC ... #pulmonary #causes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... common • Imaging: CXR ... - pulmonary opacities ... Renal Failure Treatment ... #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... of SLE versus DIL ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... skin necrosis • DIC ... #rheumatology #
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