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rheumatology management sle systemic causes differential disease druginduced summary syndrome table activation ana antinuclear antiphospholipid apls arthritis autoantibodies cell cerebritis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... Direct Coombs’ test ... #Rheumatology # ... SLE #Lupus #Erythematosus
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... • Systemic Lupus ... Erythematosus ... #Hematology #Oncology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... permeability Diagnosis ... #Erythematosus ... #cerebritis #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Erythematosus ( ... • Immunologic Workup ... #diagnosis #management
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... -15% If SLE is clinically ... suspected, tests ... #erythematosus ... #diagnosis #rheumatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... Test for the respective ... node biopsy • Clinical ... values supporting hematologic ... #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus ( ... ANA and RF (if clinical ... #diagnosis #testing
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... HIT laboratory tests ... and to adjust treatment ... #Hematology #HIT ... Thrombocytopenia #Algorithm
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